Design of reactive porous polymer supports for high throughput bioreactors: Poly(2-vinyl-4,4-dimethylazlactone-co-acrylamide-co-ethylene dimethacrylate) monoliths

Enzymatic bioreactors with both high flow characteristics and mechanical stability based on macroporous poly(2‐vinyl‐4,4‐dimethylazlactone‐co‐acrylamide‐co‐ethylene dimethacrylate) monoliths have been prepared. Covalent immobilization of trypsin on these support is achieved in a single reaction step...

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Veröffentlicht in:	Biotechnology and bioengineering 1999-01, Vol.62 (1), p.30-35
Hauptverfasser:	Xie, Shaofeng, Svec, Frantisek, Fréchet, Jean M. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	azlactone Biological and medical sciences Bioreactors Biotechnology Drug Design Enzyme immobilization Enzymes, Immobilized Fundamental and applied biological sciences. Psychology Hydrolysis Immobilization of enzymes and other molecules Immobilization techniques immobilized enzyme In Vitro Techniques Kinetics Methods. Procedures. Technologies monolith Organic polymers polymer support Polymers - chemistry Porous materials Substrate Specificity trypsin Trypsin - metabolism
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