Survival after radical treatment for transitional cell carcinoma of the bladder

AimsTo investigate survival after radical treatment for transitional cell carcinomas of the bladder.MethodsThis retrospective study included 135 patients with transitional cell carcinoma of the bladder undergoing radical cystectomy or radiotherapy at Haukeland Hospital, Bergen, Norway, during the pe...

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Veröffentlicht in:European journal of surgical oncology 1999-02, Vol.25 (1), p.66-70
Hauptverfasser: Dæhlin, L., Haukaas, S., Maartmann-Moe, H., Medby, P.C.
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container_end_page 70
container_issue 1
container_start_page 66
container_title European journal of surgical oncology
container_volume 25
creator Dæhlin, L.
Haukaas, S.
Maartmann-Moe, H.
Medby, P.C.
description AimsTo investigate survival after radical treatment for transitional cell carcinomas of the bladder.MethodsThis retrospective study included 135 patients with transitional cell carcinoma of the bladder undergoing radical cystectomy or radiotherapy at Haukeland Hospital, Bergen, Norway, during the period 1981–1986. Forty-five patients had cystectomy and 90 underwent external high-dose radiotherapy.ResultsThe overall 5- and 10-year survival rates were 39 and 23%, respectively. After cystectomy 10-year overall survival rates for superficial and muscle-infiltrating tumours were 67 and 26%; after radiotherapy, the corresponding survival rates for superficial and muscle-infiltrating tumours were 26 and 5%, respectively.ConclusionsLong-term survival and cure can be achieved after cystectomy in many patients with aggressive superficial or muscle-infiltrating bladder carcinoma. The introduction of orthotopic neobladder reconstruction should encourage the use of cystectomy in patients with aggressive superficial tumour.
doi_str_mv 10.1053/ejso.1998.0602
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Forty-five patients had cystectomy and 90 underwent external high-dose radiotherapy.ResultsThe overall 5- and 10-year survival rates were 39 and 23%, respectively. After cystectomy 10-year overall survival rates for superficial and muscle-infiltrating tumours were 67 and 26%; after radiotherapy, the corresponding survival rates for superficial and muscle-infiltrating tumours were 26 and 5%, respectively.ConclusionsLong-term survival and cure can be achieved after cystectomy in many patients with aggressive superficial or muscle-infiltrating bladder carcinoma. The introduction of orthotopic neobladder reconstruction should encourage the use of cystectomy in patients with aggressive superficial tumour.</description><identifier>ISSN: 0748-7983</identifier><identifier>EISSN: 1532-2157</identifier><identifier>DOI: 10.1053/ejso.1998.0602</identifier><identifier>PMID: 10188858</identifier><identifier>CODEN: EJSOE7</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ltd</publisher><subject>Aged ; Aged, 80 and over ; Biological and medical sciences ; bladder neoplasms ; Carcinoma, Transitional Cell - radiotherapy ; Carcinoma, Transitional Cell - surgery ; cystectomy ; Cystectomy - methods ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; radiotherapy ; Radiotherapy Dosage ; Retrospective Studies ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the urinary system ; Survival Analysis ; Treatment Outcome ; Tumors of the urinary system ; Urinary Bladder Neoplasms - radiotherapy ; Urinary Bladder Neoplasms - surgery ; Urinary tract. Prostate gland</subject><ispartof>European journal of surgical oncology, 1999-02, Vol.25 (1), p.66-70</ispartof><rights>1999 W.B. 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Forty-five patients had cystectomy and 90 underwent external high-dose radiotherapy.ResultsThe overall 5- and 10-year survival rates were 39 and 23%, respectively. After cystectomy 10-year overall survival rates for superficial and muscle-infiltrating tumours were 67 and 26%; after radiotherapy, the corresponding survival rates for superficial and muscle-infiltrating tumours were 26 and 5%, respectively.ConclusionsLong-term survival and cure can be achieved after cystectomy in many patients with aggressive superficial or muscle-infiltrating bladder carcinoma. The introduction of orthotopic neobladder reconstruction should encourage the use of cystectomy in patients with aggressive superficial tumour.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>bladder neoplasms</subject><subject>Carcinoma, Transitional Cell - radiotherapy</subject><subject>Carcinoma, Transitional Cell - surgery</subject><subject>cystectomy</subject><subject>Cystectomy - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Retrospective Studies</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the urinary system</subject><subject>Survival Analysis</subject><subject>Treatment Outcome</subject><subject>Tumors of the urinary system</subject><subject>Urinary Bladder Neoplasms - radiotherapy</subject><subject>Urinary Bladder Neoplasms - surgery</subject><subject>Urinary tract. 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Urinary tract diseases</topic><topic>radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Retrospective Studies</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the urinary system</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><topic>Tumors of the urinary system</topic><topic>Urinary Bladder Neoplasms - radiotherapy</topic><topic>Urinary Bladder Neoplasms - surgery</topic><topic>Urinary tract. Prostate gland</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dæhlin, L.</creatorcontrib><creatorcontrib>Haukaas, S.</creatorcontrib><creatorcontrib>Maartmann-Moe, H.</creatorcontrib><creatorcontrib>Medby, P.C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dæhlin, L.</au><au>Haukaas, S.</au><au>Maartmann-Moe, H.</au><au>Medby, P.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Survival after radical treatment for transitional cell carcinoma of the bladder</atitle><jtitle>European journal of surgical oncology</jtitle><addtitle>Eur J Surg Oncol</addtitle><date>1999-02-01</date><risdate>1999</risdate><volume>25</volume><issue>1</issue><spage>66</spage><epage>70</epage><pages>66-70</pages><issn>0748-7983</issn><eissn>1532-2157</eissn><coden>EJSOE7</coden><abstract>AimsTo investigate survival after radical treatment for transitional cell carcinomas of the bladder.MethodsThis retrospective study included 135 patients with transitional cell carcinoma of the bladder undergoing radical cystectomy or radiotherapy at Haukeland Hospital, Bergen, Norway, during the period 1981–1986. Forty-five patients had cystectomy and 90 underwent external high-dose radiotherapy.ResultsThe overall 5- and 10-year survival rates were 39 and 23%, respectively. After cystectomy 10-year overall survival rates for superficial and muscle-infiltrating tumours were 67 and 26%; after radiotherapy, the corresponding survival rates for superficial and muscle-infiltrating tumours were 26 and 5%, respectively.ConclusionsLong-term survival and cure can be achieved after cystectomy in many patients with aggressive superficial or muscle-infiltrating bladder carcinoma. The introduction of orthotopic neobladder reconstruction should encourage the use of cystectomy in patients with aggressive superficial tumour.</abstract><cop>Amsterdam</cop><pub>Elsevier Ltd</pub><pmid>10188858</pmid><doi>10.1053/ejso.1998.0602</doi><tpages>5</tpages></addata></record>
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subjects Aged
Aged, 80 and over
Biological and medical sciences
bladder neoplasms
Carcinoma, Transitional Cell - radiotherapy
Carcinoma, Transitional Cell - surgery
cystectomy
Cystectomy - methods
Female
Humans
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
radiotherapy
Radiotherapy Dosage
Retrospective Studies
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Survival Analysis
Treatment Outcome
Tumors of the urinary system
Urinary Bladder Neoplasms - radiotherapy
Urinary Bladder Neoplasms - surgery
Urinary tract. Prostate gland
title Survival after radical treatment for transitional cell carcinoma of the bladder
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