The Effect of Naltrexone on Taste Detection and Recognition Threshold
Eighteen healthy female volunteers were administered 50 mg naltrexone in a double-blind, placebo control study. Relative taste detection and recognition thresholds for sweet, salty, sour and bitter taste and liking for and perception of sucrose solutions were determined at baseline and 1 hour after...
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| Veröffentlicht in: | Appetite 1999-04, Vol.32 (2), p.241-249 |
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| container_title | Appetite |
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| creator | ARBISI, P.A. BILLINGTON, C.J. LEVINE, A.S. |
| description | Eighteen healthy female volunteers were administered 50 mg naltrexone in a double-blind, placebo control study. Relative taste detection and recognition thresholds for sweet, salty, sour and bitter taste and liking for and perception of sucrose solutions were determined at baseline and 1 hour after administration of naltrexone. Naltrexone did not alter relative taste detection and recognition thresholds for any of the four tastes or perception of sweetness. However, a significant, but slight, decrease in liking for sucrose solutions occurred after naltrexone administration. These findings suggest that opioid-dependent intake is independent of changes in taste perception in humans. |
| doi_str_mv | 10.1006/appe.1998.0217 |
| format | Article |
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Psychology</subject><subject>Humans</subject><subject>Memory - drug effects</subject><subject>Middle Aged</subject><subject>Naltrexone - pharmacology</subject><subject>Narcotic Antagonists - pharmacology</subject><subject>Perception - drug effects</subject><subject>Reference Values</subject><subject>Taste Threshold - drug effects</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0195-6663</issn><issn>1095-8304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1rGzEQhkVoiB0n1x7LHkpu6460Wn0cg-s0BZNAcM5Cq52tFdYrV1qX9t9Xrg3pJeQ0M8zzDsNDyEcKcwogvtjdDudUazUHRuUZmVLQdakq4B_IFGjuhRDVhFym9AIAVS3lBZnkqJbA1JQs1xssll2HbixCVzzYfoz4OwxYhKFY2zRi8RXHvPV5tkNbPKELPwb_b15vIqZN6Nsrct7ZPuH1qc7I891yvbgvV4_fvi9uV6XjAGOJoKxWHafYNpYx64B1ddNw5qRGXoFTouZtpThSV0vGOeWSC5DYVJbrRlUzcnO8u4vh5x7TaLY-Oex7O2DYJyO0EJTz-l2QSiZVzXQG50fQxZBSxM7sot_a-MdQMAfD5mDYHAybg-Ec-HS6vG-22P6HH5Vm4PMJsMnZvot2cD69cooDFyxj6ohh9vXLYzTJeRwctj5m3aYN_q0X_gJwHJV7</recordid><startdate>19990401</startdate><enddate>19990401</enddate><creator>ARBISI, P.A.</creator><creator>BILLINGTON, C.J.</creator><creator>LEVINE, A.S.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19990401</creationdate><title>The Effect of Naltrexone on Taste Detection and Recognition Threshold</title><author>ARBISI, P.A. ; BILLINGTON, C.J. ; LEVINE, A.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-e08a98f41edba22ac02f5bb42c79e430c8654d384e1c572441474607eb3a49b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Analysis of Variance</topic><topic>Biological and medical sciences</topic><topic>Double-Blind Method</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Food</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Memory - drug effects</topic><topic>Middle Aged</topic><topic>Naltrexone - pharmacology</topic><topic>Narcotic Antagonists - pharmacology</topic><topic>Perception - drug effects</topic><topic>Reference Values</topic><topic>Taste Threshold - drug effects</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ARBISI, P.A.</creatorcontrib><creatorcontrib>BILLINGTON, C.J.</creatorcontrib><creatorcontrib>LEVINE, A.S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Chemoreception Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Appetite</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ARBISI, P.A.</au><au>BILLINGTON, C.J.</au><au>LEVINE, A.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Naltrexone on Taste Detection and Recognition Threshold</atitle><jtitle>Appetite</jtitle><addtitle>Appetite</addtitle><date>1999-04-01</date><risdate>1999</risdate><volume>32</volume><issue>2</issue><spage>241</spage><epage>249</epage><pages>241-249</pages><issn>0195-6663</issn><eissn>1095-8304</eissn><coden>APPTD4</coden><abstract>Eighteen healthy female volunteers were administered 50 mg naltrexone in a double-blind, placebo control study. Relative taste detection and recognition thresholds for sweet, salty, sour and bitter taste and liking for and perception of sucrose solutions were determined at baseline and 1 hour after administration of naltrexone. Naltrexone did not alter relative taste detection and recognition thresholds for any of the four tastes or perception of sweetness. However, a significant, but slight, decrease in liking for sucrose solutions occurred after naltrexone administration. These findings suggest that opioid-dependent intake is independent of changes in taste perception in humans.</abstract><cop>Amsterdam</cop><pub>Elsevier Ltd</pub><pmid>10097028</pmid><doi>10.1006/appe.1998.0217</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0195-6663 |
| ispartof | Appetite, 1999-04, Vol.32 (2), p.241-249 |
| issn | 0195-6663 1095-8304 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Analysis of Variance Biological and medical sciences Double-Blind Method Feeding. Feeding behavior Female Food Fundamental and applied biological sciences. Psychology Humans Memory - drug effects Middle Aged Naltrexone - pharmacology Narcotic Antagonists - pharmacology Perception - drug effects Reference Values Taste Threshold - drug effects Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | The Effect of Naltrexone on Taste Detection and Recognition Threshold |
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