Antiphosphatidylserine antibodies in patients with autoimmune diseases and HIV-infected patients: effects of Tween 20 and relationship with antibodies to beta2-glycoprotein I

Antiphospholipid antibodies (aPL) react with negatively charged phospholipids, which may often be complexed with a protein cofactor such as beta2 glycoprotein (beta2GPI) and prothrombin. Cofactor requirements may be assessed by measuring antibodies to beta2GPI or by adding Tween 20 to some reagents...

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Veröffentlicht in:	Journal of clinical laboratory analysis 1999, Vol.13 (2), p.59-64
Hauptverfasser:	González, C, Lestón, A, García-Berrocal, B, Sánchez-Rodriguez, A, Martín-Oterino, J A, Alberca, I, Cordero, M, Jorge, R, Navajo, J A, González-Buitrago, J M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Antibodies, Antiphospholipid - blood Antiphospholipid Syndrome - immunology Autoimmune Diseases - immunology beta 2-Glycoprotein I Female Glycoproteins - immunology HIV Infections - immunology Humans Lupus Erythematosus, Systemic - immunology Male Middle Aged Phosphatidylserines - immunology Polysorbates - pharmacology
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