Octreotide Attenuates Impaired Microcirculation in Postischemic Pancreatitis When Administered Before Induction of Ischemia

Ischemia-reperfusion injury of the pancreas causes impairment of microcirculation leading to pancreatitis. Postischemic pancreatitis is the most common reason for graft failure in pancreas transplantation. In animal models, octreotide has been described to have beneficial effects on acute pancreatit...

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Veröffentlicht in:	Transplantation 2008-10, Vol.86 (7), p.961-967
Hauptverfasser:	WOESTE, Guido, WULLSTEIN, Christoph, MEYER, Sebastian, USADEL, Klaus H, HOPT, Ulrich T, BECHSTEIN, Wolf O, VON DOBSCHUETZ, Ernst
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Gas Analysis Capillaries - drug effects Capillaries - physiology Fundamental and applied biological sciences. Psychology Fundamental immunology Gastroenterology. Liver. Pancreas. Abdomen Infusions, Intravenous Ischemia - prevention & control Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Microcirculation - drug effects Octreotide - administration & dosage Octreotide - therapeutic use Other diseases. Semiology Pancreatitis - drug therapy Pancreatitis - etiology Rats Rats, Sprague-Dawley Reperfusion Injury - prevention & control Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology
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