Role of thyroid hormone in regulation of renal phosphate transport in young and aged rats

In the present study, we have examined the cellular mechanisms mediating the regulation of renal proximal tubular sodium-coupled inorganic phosphate (Na/Pi) transport by thyroid hormone (T3) in young and aged rats. Young hypothyroid rats showed a marked decrease in Na/Pi cotransport activity, which...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1999-04, Vol.140 (4), p.1544-1551
Hauptverfasser:	Alcalde, A I, Sarasa, M, Raldúa, D, Aramayona, J, Morales, R, Biber, J, Murer, H, Levi, M, Sorribas, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Aging - physiology Animals Biological Transport - drug effects Carrier Proteins - genetics Carrier Proteins - metabolism Gene Expression Regulation - drug effects Hyperthyroidism - metabolism Hypothyroidism - metabolism Kidney Tubules, Proximal - physiology Male Phosphates - blood Phosphates - metabolism Rats Rats, Wistar RNA, Messenger - metabolism Sodium-Phosphate Cotransporter Proteins Sodium-Phosphate Cotransporter Proteins, Type II Symporters Thyroid Hormones - physiology Triiodothyronine - pharmacology
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