Identification and Consequences of Polymorphisms in the Thyroid Hormone Receptor Alpha and Beta Genes

Objective: Genetic factors exert considerable influence on thyroid function variables. Single nucleotide polymorphisms (SNPs) in thyroid hormone pathway genes have been associated with serum thyroid parameters implying small alterations in the hypothalamus-pituitary-thyroid axis. However, little is...

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Veröffentlicht in:	Thyroid (New York, N.Y.) N.Y.), 2008-10, Vol.18 (10), p.187-1094
Hauptverfasser:	Sørensen, Helena Gásdal, van der Deure, Wendy M., Hansen, Pia Skov, Peeters, Robin P., Breteler, Monique M.B., Kyvik, Kirsten Ohm, Sørensen, Thorkild I.A., Hegedüs, Laszlo, Visser, Theo J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Denmark Female Genetic aspects Hormone receptors Humans Male Netherlands Original Studies, Reviews and Scholarly Dialog Polymorphism, Single Nucleotide Single nucleotide polymorphisms Thyroid gland Thyroid Hormone Receptors alpha - genetics Thyroid Hormone Receptors beta - genetics Thyroid Hormones - blood Thyrotropin - blood
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