Accumulation of CVIET Pfcrt allele of Plasmodium falciparum in placenta of pregnant women living in an urban area of Dakar, Senegal

Objectives Chemoprophylaxis is recommended during pregnancy to reduce the risk of placental infection. However, in areas with increasing drug resistance, it can trigger selection of resistant parasites in the placenta and increase the frequency of placental malaria. The objective of this study was t...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2008-11, Vol.62 (5), p.921-928
Hauptverfasser:	Niang, Makhtar, Marrama, Laurence, Ekala, Marie Therese, Alioune, Gaye, Tall, Adama, Ndiaye, Jean L., Sarr, Demba, Dangou, Jean Marie, Lehesran, Jean Y., Bouchier, Christiane, Mercereau-Puijalon, Odile, Jambou, Ronan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Antigens, Protozoan - genetics Biological and medical sciences Blood - parasitology Chemoprevention - methods Child Chloroquine - therapeutic use chloroquine resistance DNA, Protozoan - chemistry DNA, Protozoan - genetics Drug Resistance Female Gene Frequency Human protozoal diseases Humans Infectious diseases Malaria Malaria, Falciparum - epidemiology Malaria, Falciparum - parasitology Medical sciences Membrane Transport Proteins - genetics Merozoite Surface Protein 1 - genetics P. falciparum Parasitic diseases Pharmacology. Drug treatments Placenta - parasitology Plasmodium falciparum Plasmodium falciparum - genetics Plasmodium falciparum - isolation & purification Polymerase Chain Reaction Pregnancy Pregnant Women Protozoal diseases Protozoan Proteins - genetics Senegal - epidemiology Sequence Analysis, DNA Urban areas
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