Cloning and Expression of a Novel Lysophospholipase Which Structurally Resembles Lecithin Cholesterol Acyltransferase

Lecithin cholesterol acyltransferase (LCAT) is the key enzyme in the esterification of plasma cholesterol and in the reverse cholesterol transport on high-density lipoprotein (HDL). We have found a novel LCAT-related gene among differentially expressed cDNA fragments between two types of foam cells...

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Veröffentlicht in:	Biochemical and biophysical research communications 1999-04, Vol.257 (1), p.50-56
Hauptverfasser:	Taniyama, Yoshio, Shibata, Sachio, Kita, Shunbun, Horikoshi, Kenichi, Fuse, Hiromitsu, Shirafuji, Hideo, Sumino, Yasuhiro, Fujino, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Baculoviridae - genetics Base Sequence Blotting, Northern Blotting, Western Butyrates - metabolism Cell Line Cloning, Molecular Foam Cells - enzymology Foam Cells - metabolism Humans Isoflurophate - pharmacology Kinetics Lysophosphatidylcholines - metabolism Lysophospholipase - blood Lysophospholipase - chemistry Lysophospholipase - genetics Lysophospholipase - metabolism Molecular Sequence Data Molecular Weight Phosphatidylcholine-Sterol O-Acyltransferase - chemistry Phosphatidylcholine-Sterol O-Acyltransferase - genetics Phosphatidylcholines - metabolism Recombinant Fusion Proteins - biosynthesis Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - isolation & purification Recombinant Fusion Proteins - metabolism RNA, Messenger - analysis Sequence Homology, Amino Acid
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