Synthesis of Indoles via Domino Reaction of N-Aryl Amides and Ethyl Diazoacetate

A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.

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Veröffentlicht in:Journal of the American Chemical Society 2008-10, Vol.130 (41), p.13526-13527
Hauptverfasser: Cui, Sun-Liang, Wang, Jing, Wang, Yan-Guang
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container_end_page 13527
container_issue 41
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container_title Journal of the American Chemical Society
container_volume 130
creator Cui, Sun-Liang
Wang, Jing
Wang, Yan-Guang
description A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.
doi_str_mv 10.1021/ja805706r
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source MEDLINE; ACS Publications
subjects Amides - chemistry
Diazonium Compounds - chemistry
Indoles - chemical synthesis
Indoles - chemistry
Molecular Structure
title Synthesis of Indoles via Domino Reaction of N-Aryl Amides and Ethyl Diazoacetate
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