Synthesis of Indoles via Domino Reaction of N-Aryl Amides and Ethyl Diazoacetate

Synthesis of Indoles via Domino Reaction of N-Aryl Amides and Ethyl Diazoacetate

A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Chemical Society 2008-10, Vol.130 (41), p.13526-13527
Hauptverfasser: Cui, Sun-Liang, Wang, Jing, Wang, Yan-Guang
Format: Artikel
Sprache:eng
Schlagworte:
Amides - chemistry
Diazonium Compounds - chemistry
Indoles - chemical synthesis
Indoles - chemistry
Molecular Structure
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja805706r