T-cell receptor gene usage in patients with fibrosing alveolitis and control subjects

Background Fibrosing alveolitis is characterized by inflammation, fibrosis and increased numbers of activated CD4+ T‐cells in the lower respiratory tract. The aims of this study were to compare the T‐cell antigen receptor repertoire in the lungs of subjects with fibrosing alveolitis systemic scleros...

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Veröffentlicht in:	European journal of clinical investigation 1999-02, Vol.29 (2), p.173-181
Hauptverfasser:	Lympany, P. A., Southcott, A. M., Welsh, K. I., Black, C. M., Boylston, A. W., Du Bois, R. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Biological and medical sciences Bronchoalveolar Lavage Fluid - cytology Bronchoalveolar Lavage Fluid - immunology CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Clone Cells - immunology Cloning, Molecular Cryptogenic fibrosing alveolitis Female fibrosing alveolitis fibrosing alveolitis systemic sclerosis Gene Expression - genetics Humans Leukocytes, Mononuclear - cytology Leukocytes, Mononuclear - immunology Lung - immunology Male Medical sciences Middle Aged Pneumology Polymerase Chain Reaction Pulmonary Fibrosis - classification Pulmonary Fibrosis - immunology Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology Respiratory system : syndromes and miscellaneous diseases RNA, Messenger - genetics T-cell receptor
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