Cutaneous gamma-delta T-cell lymphoma arising in the setting of Behcet's disease
Cutaneous gamma-delta T-cell lymphoma (CGD-TCL) is an uncommon lymphoma composed of a clonal proliferation of mature activated gamma-delta T-cells expressing a cytotoxic phenotype. Malignant lymphoma is rarely associated with Behcet's disease, as only 12 cases have been reported in the literatu...
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Veröffentlicht in: | Pathologica 2008-06, Vol.100 (3), p.166-169 |
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creator | Chelly, I Limaïem, F Mekni, A Bellil, S Bellil, K Ghorbel, I B Haouet, S Zitouna, M Kchir, N |
description | Cutaneous gamma-delta T-cell lymphoma (CGD-TCL) is an uncommon lymphoma composed of a clonal proliferation of mature activated gamma-delta T-cells expressing a cytotoxic phenotype. Malignant lymphoma is rarely associated with Behcet's disease, as only 12 cases have been reported in the literature, including a case of cutaneous T-cell lymphoma. In this report, the authors present a new case of CGD-TCL emerging in the course of Behcet's disease in a 40-year-old man. Diagnosis of CGD-TCL was established based on the combination of clinical, histological, immunophenotypical and molecular findings. Through a review of the current literature, the authors analyse the unique clinicopathological, molecular and immunohistochemical features of this rare cutaneous lymphoma. |
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Through a review of the current literature, the authors analyse the unique clinicopathological, molecular and immunohistochemical features of this rare cutaneous lymphoma.</description><subject>Adult</subject><subject>Arm</subject><subject>Behcet Syndrome - complications</subject><subject>Humans</subject><subject>Lymphoma, T-Cell, Cutaneous - complications</subject><subject>Lymphoma, T-Cell, Cutaneous - pathology</subject><subject>Male</subject><subject>Skin Neoplasms - complications</subject><subject>Skin Neoplasms - pathology</subject><issn>0031-2983</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kD1PwzAYhD2AaCn8BeQJpkj-tjNCBRSpEgxljt4kr5ugOAmxM_Tf06plenTS6XR3V2TJmOSZyJ1ckNsYfxjj1ih9QxbcOcWdYEvytZ4T9DjMke4hBMhq7BLQXVZh19HuEMZmCEBhamPb72nb09QgjZjSSQ6evmBTYXqKtG4jQsQ7cu2hi3h_4Yp8v73u1pts-_n-sX7eZqNgecq8BAvGcsus8FJ77XhlZe4QGXiuKiVM6SQzFdeIua9FKY4Ai0Joa72SK_J4zh2n4XfGmIrQxlPp85rC5EZZpfXR-HAxzmXAuhinNsB0KP4_kH9Bj1bH</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>Chelly, I</creator><creator>Limaïem, F</creator><creator>Mekni, A</creator><creator>Bellil, S</creator><creator>Bellil, K</creator><creator>Ghorbel, I B</creator><creator>Haouet, S</creator><creator>Zitouna, M</creator><creator>Kchir, N</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200806</creationdate><title>Cutaneous gamma-delta T-cell lymphoma arising in the setting of Behcet's disease</title><author>Chelly, I ; Limaïem, F ; Mekni, A ; Bellil, S ; Bellil, K ; Ghorbel, I B ; Haouet, S ; Zitouna, M ; Kchir, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-f3a7a6717072f35f581c7398ee0af14c426b8306c15ee9fd2b2e9fa7e22577f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Arm</topic><topic>Behcet Syndrome - complications</topic><topic>Humans</topic><topic>Lymphoma, T-Cell, Cutaneous - complications</topic><topic>Lymphoma, T-Cell, Cutaneous - pathology</topic><topic>Male</topic><topic>Skin Neoplasms - complications</topic><topic>Skin Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chelly, I</creatorcontrib><creatorcontrib>Limaïem, F</creatorcontrib><creatorcontrib>Mekni, A</creatorcontrib><creatorcontrib>Bellil, S</creatorcontrib><creatorcontrib>Bellil, K</creatorcontrib><creatorcontrib>Ghorbel, I B</creatorcontrib><creatorcontrib>Haouet, S</creatorcontrib><creatorcontrib>Zitouna, M</creatorcontrib><creatorcontrib>Kchir, N</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Pathologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chelly, I</au><au>Limaïem, F</au><au>Mekni, A</au><au>Bellil, S</au><au>Bellil, K</au><au>Ghorbel, I B</au><au>Haouet, S</au><au>Zitouna, M</au><au>Kchir, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cutaneous gamma-delta T-cell lymphoma arising in the setting of Behcet's disease</atitle><jtitle>Pathologica</jtitle><addtitle>Pathologica</addtitle><date>2008-06</date><risdate>2008</risdate><volume>100</volume><issue>3</issue><spage>166</spage><epage>169</epage><pages>166-169</pages><issn>0031-2983</issn><abstract>Cutaneous gamma-delta T-cell lymphoma (CGD-TCL) is an uncommon lymphoma composed of a clonal proliferation of mature activated gamma-delta T-cells expressing a cytotoxic phenotype. 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subjects | Adult Arm Behcet Syndrome - complications Humans Lymphoma, T-Cell, Cutaneous - complications Lymphoma, T-Cell, Cutaneous - pathology Male Skin Neoplasms - complications Skin Neoplasms - pathology |
title | Cutaneous gamma-delta T-cell lymphoma arising in the setting of Behcet's disease |
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