Vasculitis in the Palmerston North mouse model of lupus: Phenotype and cytokine production profile of infiltrating cells

Objective To define the phenotype of cells in the perivascular and vascular infiltrates of Palmerston North (PN) mice and the cytokines that those cells produce. Methods Immunohistologic analysis, flow cytometric analysis, and reverse transcriptase–polymerase chain reaction (RT‐PCR) studies were per...

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Veröffentlicht in:	Arthritis and rheumatism 1999-03, Vol.42 (3), p.561-568
Hauptverfasser:	Luzina, Irina G., Knitzer, Robert H., Atamas, Sergei P., Gause, William C., Papadimitriou, John C., Sztein, Marcelo B., Storrer, Catherine E., Handwerger, Barry S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - immunology Biological and medical sciences Disease Models, Animal Female Gene Expression - immunology Interferon-gamma - genetics Interleukin-1 - genetics Interleukin-10 - genetics Interleukin-2 - genetics Interleukin-4 - genetics Interleukin-6 - genetics Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Medical sciences Mice Mice, Inbred DBA Mice, Inbred MRL lpr Mice, Inbred NZB Mice, Inbred Strains Phenotype Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis T-Lymphocytes - immunology Transforming Growth Factor beta - genetics Vasculitis - genetics Vasculitis - immunology
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