Conduction disturbances and increased atrial vulnerability in connexin40-deficient mice analyzed by transesophageal stimulation

Recently, it has been reported that connexin40 (Cx40) deficiency in targeted mouse mutants is associated with a prolongation of P-wave and QRS complex duration on surface electrograms. The specific effects of Cx40 deficiency on sinus node function, sinoatrial, and atrioventricular conduction propert...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1999-03, Vol.99 (11), p.1508-1515
Hauptverfasser:	HAGENDORFF, A, SCHUMACHER, B, KIRCHHOFF, S, LÜDERITZ, B, WILLECKE, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - genetics Arrhythmias, Cardiac - physiopathology Biological and medical sciences Cardiac dysrhythmias Cardiology. Vascular system Connexins - deficiency Connexins - genetics Connexins - physiology Electric Stimulation Electrocardiography Female Gap Junction alpha-5 Protein Heart Heart Block - etiology Heart Block - genetics Heart Block - physiopathology Heart Conduction System - physiopathology Male Medical sciences Mice Mice, Knockout Sinoatrial Block - etiology Sinoatrial Block - genetics Sinoatrial Block - physiopathology Tachycardia, Supraventricular - etiology Tachycardia, Supraventricular - genetics Tachycardia, Supraventricular - physiopathology
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