Usefulness of intraoperative fluorescence imaging to evaluate local anatomy in hepatobiliary surgery
Background/Purpose One of the major complications encountered in hepatobiliary surgery is the incidence of bile duct and blood vessel injuries. It is sometimes difficult during surgery to evaluate the local anatomy corresponding to hepatic arteries and bile ducts. We investigated the potential utili...
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| Veröffentlicht in: | Journal of Hepato‐Biliary‐Pancreatic Surgery 2008-09, Vol.15 (5), p.508-514 |
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| container_title | Journal of Hepato‐Biliary‐Pancreatic Surgery |
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| creator | Mitsuhashi, Noboru Kimura, Fumio Shimizu, Hiroaki Imamaki, Mizuho Yoshidome, Hiroyuki Ohtsuka, Masayuki Kato, Atsushi Yoshitomi, Hideyuki Nozawa, Satoshi Furukawa, Katsunori Takeuchi, Dan Takayashiki, Tsukasa Suda, Kosuke Igarashi, Tatsuo Miyazaki, Masaru |
| description | Background/Purpose
One of the major complications encountered in hepatobiliary surgery is the incidence of bile duct and blood vessel injuries. It is sometimes difficult during surgery to evaluate the local anatomy corresponding to hepatic arteries and bile ducts. We investigated the potential utility of an infrared camera system as a tool for evaluating local anatomy during hepatobiliary surgery.
Methods
An infrared camera system was used to detect indocyanine green fluorescence in vitro. We also employed this system for the intraoperative fluorescence imaging of the arteries and biliary system in a pig. Further, we evaluated blood flow in the hepatic artery, portal vein, and liver parenchyma during a human liver transplant and we investigated local anatomy in patients undergoing cholecystectomy.
Results
Fluorescence confirmed that indocyanine green was distributed in serum and bile. In the pig study, we confirmed the fluorescence of the biliary system for more than 1 h. In the liver transplant recipient, blood flow in the hepatic artery and portal vein was confirmed around the anastomosis. In most of the patients undergoing cholecystectomy, fluorescence was observed in the gallbladder, cystic and common bile ducts, and hepatic and cystic arteries.
Conclusions
Intraoperative fluorescence imaging in hepatobiliary surgery facilitates better understanding of the anatomy of arteries, the portal vein, and bile ducts. |
| doi_str_mv | 10.1007/s00534-007-1307-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69639387</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69639387</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5096-76056f87d58849a60c02dc92a40525037c2159d7753d78daafe6aafc087077ac3</originalsourceid><addsrcrecordid>eNqFkE1P3DAQhq0KVBboD-il8olbYBzHHzm2iLIgJDjA2TLOZBvkjVM7WZR_X6-yUm9wGc_hfV6NH0K-M7hkAOoqAQheFXktGM9DfCErVnFZgKzZEVlBXVUFY1KekNOU3gCYElp9JSdMay41iBVpXhK2k-8xJRpa2vVjtGHAaMduh7T1U4iYHPYOabe1m67f0DFQ3Fk_2RGpD856ans7hu2cafoHh7y_dr6zcaZpihuM8zk5bq1P-O3wnpGX3zfP1-vi4fH27vrnQ-EE1LJQEoRstWqE1lVtJTgoG1eXtgJRCuDKlUzUjVKCN0o31rYo83CgFShlHT8jF0vvEMPfCdNotl0-3nvbY5iSkbXkNdcqB9kSdDGkFLE1Q8zfi7NhYPZqzaLW7Ne9WiMy8-NQPr1usflPHFzmgFoC753H-fNGc7_-9cSqUmayXMiUoT4bM29hin1W9cE9_wD9zpXm</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69639387</pqid></control><display><type>article</type><title>Usefulness of intraoperative fluorescence imaging to evaluate local anatomy in hepatobiliary surgery</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Mitsuhashi, Noboru ; Kimura, Fumio ; Shimizu, Hiroaki ; Imamaki, Mizuho ; Yoshidome, Hiroyuki ; Ohtsuka, Masayuki ; Kato, Atsushi ; Yoshitomi, Hideyuki ; Nozawa, Satoshi ; Furukawa, Katsunori ; Takeuchi, Dan ; Takayashiki, Tsukasa ; Suda, Kosuke ; Igarashi, Tatsuo ; Miyazaki, Masaru</creator><creatorcontrib>Mitsuhashi, Noboru ; Kimura, Fumio ; Shimizu, Hiroaki ; Imamaki, Mizuho ; Yoshidome, Hiroyuki ; Ohtsuka, Masayuki ; Kato, Atsushi ; Yoshitomi, Hideyuki ; Nozawa, Satoshi ; Furukawa, Katsunori ; Takeuchi, Dan ; Takayashiki, Tsukasa ; Suda, Kosuke ; Igarashi, Tatsuo ; Miyazaki, Masaru</creatorcontrib><description>Background/Purpose
One of the major complications encountered in hepatobiliary surgery is the incidence of bile duct and blood vessel injuries. It is sometimes difficult during surgery to evaluate the local anatomy corresponding to hepatic arteries and bile ducts. We investigated the potential utility of an infrared camera system as a tool for evaluating local anatomy during hepatobiliary surgery.
Methods
An infrared camera system was used to detect indocyanine green fluorescence in vitro. We also employed this system for the intraoperative fluorescence imaging of the arteries and biliary system in a pig. Further, we evaluated blood flow in the hepatic artery, portal vein, and liver parenchyma during a human liver transplant and we investigated local anatomy in patients undergoing cholecystectomy.
Results
Fluorescence confirmed that indocyanine green was distributed in serum and bile. In the pig study, we confirmed the fluorescence of the biliary system for more than 1 h. In the liver transplant recipient, blood flow in the hepatic artery and portal vein was confirmed around the anastomosis. In most of the patients undergoing cholecystectomy, fluorescence was observed in the gallbladder, cystic and common bile ducts, and hepatic and cystic arteries.
Conclusions
Intraoperative fluorescence imaging in hepatobiliary surgery facilitates better understanding of the anatomy of arteries, the portal vein, and bile ducts.</description><identifier>ISSN: 0944-1166</identifier><identifier>EISSN: 1436-0691</identifier><identifier>EISSN: 1868-6982</identifier><identifier>DOI: 10.1007/s00534-007-1307-5</identifier><identifier>PMID: 18836805</identifier><language>eng</language><publisher>Japan: Springer Japan</publisher><subject>Abdominal Surgery ; Animals ; biliary tract ; Biliary Tract - anatomy & histology ; Biliary Tract Surgical Procedures ; cholangiogram ; Cholecystectomy ; Coloring Agents ; Fluorescence ; fluorescence imaging ; Gastroenterology ; Hepatology ; Humans ; In Vitro Techniques ; indocyanine green ; Indocyanine Green - analogs & derivatives ; infrared camera ; Infrared Rays ; Laparotomy ; Liver - anatomy & histology ; Liver - surgery ; Liver Transplantation ; Male ; Medicine ; Medicine & Public Health ; Original Article ; Surgical Oncology ; Swine</subject><ispartof>Journal of Hepato‐Biliary‐Pancreatic Surgery, 2008-09, Vol.15 (5), p.508-514</ispartof><rights>Springer Japan 2008</rights><rights>2008 Japanese Society of Hepato‐Biliary‐Pancreatic Surgery</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5096-76056f87d58849a60c02dc92a40525037c2159d7753d78daafe6aafc087077ac3</citedby><cites>FETCH-LOGICAL-c5096-76056f87d58849a60c02dc92a40525037c2159d7753d78daafe6aafc087077ac3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1007%2Fs00534-007-1307-5$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1007%2Fs00534-007-1307-5$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27922,27923,45572,45573</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18836805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mitsuhashi, Noboru</creatorcontrib><creatorcontrib>Kimura, Fumio</creatorcontrib><creatorcontrib>Shimizu, Hiroaki</creatorcontrib><creatorcontrib>Imamaki, Mizuho</creatorcontrib><creatorcontrib>Yoshidome, Hiroyuki</creatorcontrib><creatorcontrib>Ohtsuka, Masayuki</creatorcontrib><creatorcontrib>Kato, Atsushi</creatorcontrib><creatorcontrib>Yoshitomi, Hideyuki</creatorcontrib><creatorcontrib>Nozawa, Satoshi</creatorcontrib><creatorcontrib>Furukawa, Katsunori</creatorcontrib><creatorcontrib>Takeuchi, Dan</creatorcontrib><creatorcontrib>Takayashiki, Tsukasa</creatorcontrib><creatorcontrib>Suda, Kosuke</creatorcontrib><creatorcontrib>Igarashi, Tatsuo</creatorcontrib><creatorcontrib>Miyazaki, Masaru</creatorcontrib><title>Usefulness of intraoperative fluorescence imaging to evaluate local anatomy in hepatobiliary surgery</title><title>Journal of Hepato‐Biliary‐Pancreatic Surgery</title><addtitle>J Hepatobiliary Pancreat Surg</addtitle><addtitle>J Hepatobiliary Pancreat Surg</addtitle><description>Background/Purpose
One of the major complications encountered in hepatobiliary surgery is the incidence of bile duct and blood vessel injuries. It is sometimes difficult during surgery to evaluate the local anatomy corresponding to hepatic arteries and bile ducts. We investigated the potential utility of an infrared camera system as a tool for evaluating local anatomy during hepatobiliary surgery.
Methods
An infrared camera system was used to detect indocyanine green fluorescence in vitro. We also employed this system for the intraoperative fluorescence imaging of the arteries and biliary system in a pig. Further, we evaluated blood flow in the hepatic artery, portal vein, and liver parenchyma during a human liver transplant and we investigated local anatomy in patients undergoing cholecystectomy.
Results
Fluorescence confirmed that indocyanine green was distributed in serum and bile. In the pig study, we confirmed the fluorescence of the biliary system for more than 1 h. In the liver transplant recipient, blood flow in the hepatic artery and portal vein was confirmed around the anastomosis. In most of the patients undergoing cholecystectomy, fluorescence was observed in the gallbladder, cystic and common bile ducts, and hepatic and cystic arteries.
Conclusions
Intraoperative fluorescence imaging in hepatobiliary surgery facilitates better understanding of the anatomy of arteries, the portal vein, and bile ducts.</description><subject>Abdominal Surgery</subject><subject>Animals</subject><subject>biliary tract</subject><subject>Biliary Tract - anatomy & histology</subject><subject>Biliary Tract Surgical Procedures</subject><subject>cholangiogram</subject><subject>Cholecystectomy</subject><subject>Coloring Agents</subject><subject>Fluorescence</subject><subject>fluorescence imaging</subject><subject>Gastroenterology</subject><subject>Hepatology</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>indocyanine green</subject><subject>Indocyanine Green - analogs & derivatives</subject><subject>infrared camera</subject><subject>Infrared Rays</subject><subject>Laparotomy</subject><subject>Liver - anatomy & histology</subject><subject>Liver - surgery</subject><subject>Liver Transplantation</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><subject>Surgical Oncology</subject><subject>Swine</subject><issn>0944-1166</issn><issn>1436-0691</issn><issn>1868-6982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P3DAQhq0KVBboD-il8olbYBzHHzm2iLIgJDjA2TLOZBvkjVM7WZR_X6-yUm9wGc_hfV6NH0K-M7hkAOoqAQheFXktGM9DfCErVnFZgKzZEVlBXVUFY1KekNOU3gCYElp9JSdMay41iBVpXhK2k-8xJRpa2vVjtGHAaMduh7T1U4iYHPYOabe1m67f0DFQ3Fk_2RGpD856ans7hu2cafoHh7y_dr6zcaZpihuM8zk5bq1P-O3wnpGX3zfP1-vi4fH27vrnQ-EE1LJQEoRstWqE1lVtJTgoG1eXtgJRCuDKlUzUjVKCN0o31rYo83CgFShlHT8jF0vvEMPfCdNotl0-3nvbY5iSkbXkNdcqB9kSdDGkFLE1Q8zfi7NhYPZqzaLW7Ne9WiMy8-NQPr1usflPHFzmgFoC753H-fNGc7_-9cSqUmayXMiUoT4bM29hin1W9cE9_wD9zpXm</recordid><startdate>200809</startdate><enddate>200809</enddate><creator>Mitsuhashi, Noboru</creator><creator>Kimura, Fumio</creator><creator>Shimizu, Hiroaki</creator><creator>Imamaki, Mizuho</creator><creator>Yoshidome, Hiroyuki</creator><creator>Ohtsuka, Masayuki</creator><creator>Kato, Atsushi</creator><creator>Yoshitomi, Hideyuki</creator><creator>Nozawa, Satoshi</creator><creator>Furukawa, Katsunori</creator><creator>Takeuchi, Dan</creator><creator>Takayashiki, Tsukasa</creator><creator>Suda, Kosuke</creator><creator>Igarashi, Tatsuo</creator><creator>Miyazaki, Masaru</creator><general>Springer Japan</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200809</creationdate><title>Usefulness of intraoperative fluorescence imaging to evaluate local anatomy in hepatobiliary surgery</title><author>Mitsuhashi, Noboru ; Kimura, Fumio ; Shimizu, Hiroaki ; Imamaki, Mizuho ; Yoshidome, Hiroyuki ; Ohtsuka, Masayuki ; Kato, Atsushi ; Yoshitomi, Hideyuki ; Nozawa, Satoshi ; Furukawa, Katsunori ; Takeuchi, Dan ; Takayashiki, Tsukasa ; Suda, Kosuke ; Igarashi, Tatsuo ; Miyazaki, Masaru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5096-76056f87d58849a60c02dc92a40525037c2159d7753d78daafe6aafc087077ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Abdominal Surgery</topic><topic>Animals</topic><topic>biliary tract</topic><topic>Biliary Tract - anatomy & histology</topic><topic>Biliary Tract Surgical Procedures</topic><topic>cholangiogram</topic><topic>Cholecystectomy</topic><topic>Coloring Agents</topic><topic>Fluorescence</topic><topic>fluorescence imaging</topic><topic>Gastroenterology</topic><topic>Hepatology</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>indocyanine green</topic><topic>Indocyanine Green - analogs & derivatives</topic><topic>infrared camera</topic><topic>Infrared Rays</topic><topic>Laparotomy</topic><topic>Liver - anatomy & histology</topic><topic>Liver - surgery</topic><topic>Liver Transplantation</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><topic>Surgical Oncology</topic><topic>Swine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mitsuhashi, Noboru</creatorcontrib><creatorcontrib>Kimura, Fumio</creatorcontrib><creatorcontrib>Shimizu, Hiroaki</creatorcontrib><creatorcontrib>Imamaki, Mizuho</creatorcontrib><creatorcontrib>Yoshidome, Hiroyuki</creatorcontrib><creatorcontrib>Ohtsuka, Masayuki</creatorcontrib><creatorcontrib>Kato, Atsushi</creatorcontrib><creatorcontrib>Yoshitomi, Hideyuki</creatorcontrib><creatorcontrib>Nozawa, Satoshi</creatorcontrib><creatorcontrib>Furukawa, Katsunori</creatorcontrib><creatorcontrib>Takeuchi, Dan</creatorcontrib><creatorcontrib>Takayashiki, Tsukasa</creatorcontrib><creatorcontrib>Suda, Kosuke</creatorcontrib><creatorcontrib>Igarashi, Tatsuo</creatorcontrib><creatorcontrib>Miyazaki, Masaru</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Hepato‐Biliary‐Pancreatic Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mitsuhashi, Noboru</au><au>Kimura, Fumio</au><au>Shimizu, Hiroaki</au><au>Imamaki, Mizuho</au><au>Yoshidome, Hiroyuki</au><au>Ohtsuka, Masayuki</au><au>Kato, Atsushi</au><au>Yoshitomi, Hideyuki</au><au>Nozawa, Satoshi</au><au>Furukawa, Katsunori</au><au>Takeuchi, Dan</au><au>Takayashiki, Tsukasa</au><au>Suda, Kosuke</au><au>Igarashi, Tatsuo</au><au>Miyazaki, Masaru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Usefulness of intraoperative fluorescence imaging to evaluate local anatomy in hepatobiliary surgery</atitle><jtitle>Journal of Hepato‐Biliary‐Pancreatic Surgery</jtitle><stitle>J Hepatobiliary Pancreat Surg</stitle><addtitle>J Hepatobiliary Pancreat Surg</addtitle><date>2008-09</date><risdate>2008</risdate><volume>15</volume><issue>5</issue><spage>508</spage><epage>514</epage><pages>508-514</pages><issn>0944-1166</issn><eissn>1436-0691</eissn><eissn>1868-6982</eissn><abstract>Background/Purpose
One of the major complications encountered in hepatobiliary surgery is the incidence of bile duct and blood vessel injuries. It is sometimes difficult during surgery to evaluate the local anatomy corresponding to hepatic arteries and bile ducts. We investigated the potential utility of an infrared camera system as a tool for evaluating local anatomy during hepatobiliary surgery.
Methods
An infrared camera system was used to detect indocyanine green fluorescence in vitro. We also employed this system for the intraoperative fluorescence imaging of the arteries and biliary system in a pig. Further, we evaluated blood flow in the hepatic artery, portal vein, and liver parenchyma during a human liver transplant and we investigated local anatomy in patients undergoing cholecystectomy.
Results
Fluorescence confirmed that indocyanine green was distributed in serum and bile. In the pig study, we confirmed the fluorescence of the biliary system for more than 1 h. In the liver transplant recipient, blood flow in the hepatic artery and portal vein was confirmed around the anastomosis. In most of the patients undergoing cholecystectomy, fluorescence was observed in the gallbladder, cystic and common bile ducts, and hepatic and cystic arteries.
Conclusions
Intraoperative fluorescence imaging in hepatobiliary surgery facilitates better understanding of the anatomy of arteries, the portal vein, and bile ducts.</abstract><cop>Japan</cop><pub>Springer Japan</pub><pmid>18836805</pmid><doi>10.1007/s00534-007-1307-5</doi><tpages>7</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Abdominal Surgery Animals biliary tract Biliary Tract - anatomy & histology Biliary Tract Surgical Procedures cholangiogram Cholecystectomy Coloring Agents Fluorescence fluorescence imaging Gastroenterology Hepatology Humans In Vitro Techniques indocyanine green Indocyanine Green - analogs & derivatives infrared camera Infrared Rays Laparotomy Liver - anatomy & histology Liver - surgery Liver Transplantation Male Medicine Medicine & Public Health Original Article Surgical Oncology Swine |
| title | Usefulness of intraoperative fluorescence imaging to evaluate local anatomy in hepatobiliary surgery |
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