The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines

Viral fusion proteins are required for the fusion of viral and host membranes for all enveloped viruses. The structure of the Baculovirus postfusion form of glycoprotein gp64, a class III fusion protein, explains its ability to fuse with many different cell types, and structural comparisons suggest...

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Veröffentlicht in:	Nature structural & molecular biology 2008-10, Vol.15 (10), p.1024-1030
Hauptverfasser:	Kadlec, Jan, Loureiro, Silvia, Abrescia, Nicola G A, Stuart, David I, Jones, Ian M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baculoviridae - chemistry Baculoviridae - genetics Baculoviridae - metabolism Baculovirus Baculoviruses Biochemistry Biological Microscopy Biological properties Biomedical and Life Sciences Cell Line Crystal structure Crystallography, X-Ray Genetic aspects Glycoproteins Herpes simplex virus 1 Hydrogen-Ion Concentration Insects Life Sciences Mammals Membrane Biology Membrane Fusion Models, Molecular Molecular biology Peptides Physiological aspects Protein Structure Protein Structure, Quaternary Protein Structure, Tertiary Proteins Spodoptera Structural Homology, Protein Structure Vesicular stomatitis virus Viral Fusion Proteins - chemistry Viral Fusion Proteins - classification Viral Fusion Proteins - genetics Viral Fusion Proteins - metabolism Virus Internalization Viruses
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