Hepatocyte Growth Factor Is a Major Mediator in Heparin-Induced Angiogenesis

Heparin has a potent angiogenic effect in experimental animals and patients with ischemic diseases; however, the precise mechanism behind this angiogenesis remains to be clarified. The aim of this study was to determine whether the administration of heparin affects the levels of heparin-binding angi...

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Veröffentlicht in:	Biochemical and biophysical research communications 1999-02, Vol.255 (1), p.80-87
Hauptverfasser:	Okada, Masaharu, Matsumori, Akira, Ono, Koh, Miyamoto, Tadashi, Takahashi, Mamoru, Sasayama, Shigetake
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cell Differentiation - drug effects Cells, Cultured Endothelial Growth Factors - blood Endothelium, Vascular - cytology Endothelium, Vascular - drug effects Female Fibrinolytic Agents - pharmacology Fibroblast Growth Factor 2 - blood Heparin - pharmacology Hepatocyte Growth Factor - blood Humans Lymphokines - blood Male Middle Aged Neovascularization, Physiologic - drug effects Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors
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