Cloning and Characterization of a Mammalian Prenyl Protein-specific Protease

Proteins containing C-terminal âC AAX â sequence motifs undergo three sequential post-translational processing steps: modification of the cysteine with either a 15-carbon farnesyl or 20-carbon geranylgeranyl isoprenyl lipid, proteolysis of the C-terminal - AAX tripeptide, and methylation of the...

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Veröffentlicht in:	The Journal of biological chemistry 1999-03, Vol.274 (13), p.8379-8382
Hauptverfasser:	Otto, J C, Kim, E, Young, S G, Casey, P J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cell Line Cloning, Molecular Endopeptidases - chemistry Endopeptidases - genetics Humans Kinetics Metalloendopeptidases Molecular Sequence Data Proprotein Convertases Protein Prenylation - genetics Recombinant Proteins - genetics RNA, Messenger - metabolism Saccharomyces cerevisiae Proteins Sequence Alignment Sequence Analysis, DNA
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