Short Courses of Zidovudine and Perinatal Transmission of HIV
To the Editor: As mentioned by Wade et al. in their paper (Nov. 12 issue), 1 we have also investigated the effects of the partial use of the AIDS Clinical Trials Group (ACTG) protocol regimen 076 on the rates of perinatal transmission of the human immunodeficiency virus (HIV). 2 Our results, with tw...
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| Veröffentlicht in: | The New England journal of medicine 1999-04, Vol.340 (13), p.1040-1043 |
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| container_title | The New England journal of medicine |
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| creator | Fiscus, S A Schoenbach, V J Wilfert, C |
| description | To the Editor:
As mentioned by Wade et al. in their paper (Nov. 12 issue),
1
we have also investigated the effects of the partial use of the AIDS Clinical Trials Group (ACTG) protocol regimen 076 on the rates of perinatal transmission of the human immunodeficiency virus (HIV).
2
Our results, with two additional years of data, are shown in Table 1 and in most cases are very similar to the results of Wade et al. We found that when treatment was begun during the prenatal period, the rate of transmission was 3.2 percent, as compared with the 6.1 percent rate reported by the . . . |
| doi_str_mv | 10.1056/NEJM199904013401312 |
| format | Article |
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As mentioned by Wade et al. in their paper (Nov. 12 issue),
1
we have also investigated the effects of the partial use of the AIDS Clinical Trials Group (ACTG) protocol regimen 076 on the rates of perinatal transmission of the human immunodeficiency virus (HIV).
2
Our results, with two additional years of data, are shown in Table 1 and in most cases are very similar to the results of Wade et al. We found that when treatment was begun during the prenatal period, the rate of transmission was 3.2 percent, as compared with the 6.1 percent rate reported by the . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199904013401312</identifier><identifier>PMID: 10189281</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>AIDS/HIV ; Anti-HIV Agents - administration & dosage ; Drug Administration Schedule ; Female ; HIV Infections - diagnosis ; HIV Infections - drug therapy ; HIV Infections - transmission ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical - prevention & control ; Polymerase Chain Reaction ; Pregnancy ; Pregnancy Complications, Infectious - drug therapy ; Zidovudine - administration & dosage</subject><ispartof>The New England journal of medicine, 1999-04, Vol.340 (13), p.1040-1043</ispartof><rights>Copyright © 1999 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-92d014b8912aeb47163c87117ad4c6704a1c5d346dd16cea5477bbfeaf93cb93</citedby><cites>FETCH-LOGICAL-c403t-92d014b8912aeb47163c87117ad4c6704a1c5d346dd16cea5477bbfeaf93cb93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199904013401312$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/223951599?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,782,786,2761,2762,26110,27931,27932,52389,54071,64392,64394,64396,72476</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10189281$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fiscus, S A</creatorcontrib><creatorcontrib>Schoenbach, V J</creatorcontrib><creatorcontrib>Wilfert, C</creatorcontrib><title>Short Courses of Zidovudine and Perinatal Transmission of HIV</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
As mentioned by Wade et al. in their paper (Nov. 12 issue),
1
we have also investigated the effects of the partial use of the AIDS Clinical Trials Group (ACTG) protocol regimen 076 on the rates of perinatal transmission of the human immunodeficiency virus (HIV).
2
Our results, with two additional years of data, are shown in Table 1 and in most cases are very similar to the results of Wade et al. We found that when treatment was begun during the prenatal period, the rate of transmission was 3.2 percent, as compared with the 6.1 percent rate reported by the . . .</description><subject>AIDS/HIV</subject><subject>Anti-HIV Agents - administration & dosage</subject><subject>Drug Administration Schedule</subject><subject>Female</subject><subject>HIV Infections - diagnosis</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - transmission</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infectious Disease Transmission, Vertical - prevention & control</subject><subject>Polymerase Chain Reaction</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - drug therapy</subject><subject>Zidovudine - administration & dosage</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kE9LxDAQxYMo7rr6CQQpHrxINZOkaXPwIMvqrqx_wMWDl5ImKXbZppq0gt_elO5BRBwY5vKbN28eQseALwAn_PJhdncPQgjMMNC-geygMSSUxoxhvovGGJMsZqmgI3Tg_RqHAib20QgwZIJkMEZXz2-Na6Np0zlvfNSU0Wulm89OV9ZE0uroybjKylZuopWT1teV91Vje3C-eDlEe6XceHO0nRO0upmtpvN4-Xi7mF4vY8UwbWNBdDhcZAKINAVLgVOVpQCp1EzxFDMJKtGUca2BKyMTlqZFURpZCqoKQSfobJB9d81HZ3ybBxvKbDbSmqbzORecUkzSAJ7-AtfhMRus5YRQkUAiejU6QMo13jtT5u-uqqX7ygHnfbL5H8mGrZOtdFfURv_YGaIMwPkA1LXPrVnX_8p9A2j5fgU</recordid><startdate>19990401</startdate><enddate>19990401</enddate><creator>Fiscus, S A</creator><creator>Schoenbach, V J</creator><creator>Wilfert, C</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>19990401</creationdate><title>Short Courses of Zidovudine and Perinatal Transmission of HIV</title><author>Fiscus, S A ; 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As mentioned by Wade et al. in their paper (Nov. 12 issue),
1
we have also investigated the effects of the partial use of the AIDS Clinical Trials Group (ACTG) protocol regimen 076 on the rates of perinatal transmission of the human immunodeficiency virus (HIV).
2
Our results, with two additional years of data, are shown in Table 1 and in most cases are very similar to the results of Wade et al. We found that when treatment was begun during the prenatal period, the rate of transmission was 3.2 percent, as compared with the 6.1 percent rate reported by the . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>10189281</pmid><doi>10.1056/NEJM199904013401312</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | AIDS/HIV Anti-HIV Agents - administration & dosage Drug Administration Schedule Female HIV Infections - diagnosis HIV Infections - drug therapy HIV Infections - transmission Humans Infant, Newborn Infectious Disease Transmission, Vertical - prevention & control Polymerase Chain Reaction Pregnancy Pregnancy Complications, Infectious - drug therapy Zidovudine - administration & dosage |
| title | Short Courses of Zidovudine and Perinatal Transmission of HIV |
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