Insulin-like growth factor binding protein-3: its biological effect on bovine granulosa cells

This study was aimed at testing the hypothesis that insulin-like growth factor binding protein (IGFBP)-3 can modulate hormone-dependent differentiation of granulosa cells in vitro. Granulosa cells from small (1 to 5 mm) follicles were collected from cattle, cultured for 2 d in medium containing 10%...

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Veröffentlicht in:	Domestic animal endocrinology 1999, Vol.16 (1), p.19-29
Hauptverfasser:	Spicer, L.J, Chamberlain, C.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals binding binding proteins Cattle cell division cell proliferation Cells, Cultured cultured cells estradiol Estradiol - biosynthesis Female Follicle Stimulating Hormone - pharmacology follicle-stimulating hormone granulosa cells Granulosa Cells - drug effects Granulosa Cells - metabolism hormonal regulation inhibition insulin-like growth factor Insulin-Like Growth Factor Binding Protein 3 - pharmacology Insulin-Like Growth Factor I - administration & dosage Insulin-Like Growth Factor I - metabolism Insulin-Like Growth Factor I - pharmacology progesterone Progesterone - biosynthesis Receptor, IGF Type 1 - drug effects Receptor, IGF Type 1 - metabolism Recombinant Proteins - pharmacology steroidogenesis
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