Prognostic Significance of K-ras Codon 12 Mutations in Patients With Resected Stage I and II Non–Small-Cell Lung Cancer

The aim of this study was to investigate the prognostic importance of codon 12 K-ras mutations in patients with early-stage non-small-cell lung cancer (NSCLC). We identified 260 patients with surgically resected stage I (n = 193) and stage II (n = 67) NSCLC with at least a 5-year follow-up. We perfo...

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Veröffentlicht in:	Journal of clinical oncology 1999-02, Vol.17 (2), p.668-675
Hauptverfasser:	GRAZIANO, S. L, GAMBLE, G. P, NEWMAN, N. B, ABBOTT, L. Z, ROONEY, M, MOOKHERJEE, S, LAMB, M. L, KOHMAN, L. J, POIESZ, B. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Blotting, Southern Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - surgery Codon Disease-Free Survival DNA, Neoplasm - analysis DNA, Neoplasm - genetics Female Genes, ras Humans Lung Neoplasms - genetics Lung Neoplasms - pathology Lung Neoplasms - surgery Male Medical sciences Middle Aged Mutation Neoplasm Staging Pneumology Polymerase Chain Reaction Prognosis Tumors of the respiratory system and mediastinum
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