Activation of Nitric Oxide Signaling through Muscarinic Receptors in Submandibular Glands by Primary Sjögren Syndrome Antibodies

Primary Sjögren Syndrome is a chronic autoimmune disease characterized by exocrine gland dysfunction. Here we present evidence of the activation of nitric oxide signaling cascade by circulating antibodies of patients with Sjögren Syndrome in rat submandibular glands. Constitutive nitric oxide syntha...

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