Evaluation and improvement of multiple sequence methods for protein secondary structure prediction

A new dataset of 396 protein domains is developed and used to evaluate the performance of the protein secondary structure prediction algorithms DSC, PHD, NNSSP, and PREDATOR. The maximum theoretical Q3 accuracy for combination of these methods is shown to be 78%. A simple consensus prediction on the...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 1999-03, Vol.34 (4), p.508-519
Hauptverfasser:	Cuff, James A., Barton, Geoffrey J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms benchmarks combination of methods Computer Simulation Databases, Factual Models, Statistical protein Protein Structure, Secondary Reproducibility of Results secondary structure prediction Sequence Alignment
Online-Zugang:	Volltext
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