A Randomized, Double-Blind, Placebo-Controlled Pilot Study of Simvastatin in Aneurysmal Subarachnoid Hemorrhage

Studies suggest statins ameliorate aneurysmal subarachnoid hemorrhage (SAH)-induced cerebral vasospasm and ischemic complications. We tested safety and feasibility of simvastatin 80 mg/d for vasospasm prevention in SAH patients. Thirty-nine statin-naïve Fisher grade 3 SAH subjects were double-blind...

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Veröffentlicht in:	Stroke (1970) 2008-10, Vol.39 (10), p.2891-2893
Hauptverfasser:	CHOU, Sherry H.-Y, SMITH, Eric E, BADJATIA, Neeraj, NOGUEIRA, Raul G, SIMS, John R, OGILVY, Christopher S, RORDORF, Guy A, AYATA, Cenk
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Double-Blind Method Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Male Medical sciences Middle Aged Muscle Neurology Pharmacology. Drug treatments Pilot Projects Simvastatin - therapeutic use Subarachnoid Hemorrhage - complications Subarachnoid Hemorrhage - drug therapy Vascular diseases and vascular malformations of the nervous system Vasospasm, Intracranial - etiology Vasospasm, Intracranial - prevention & control
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