Total Synthesis of (-)-Allosecurinine

Safe and secure: An efficient methodology which provides access to homochiral 2,5‐cis pyrrolidines in excellent yields starting from chiral alkoxyamine cyclopropanes was used in the total synthesis of (−)‐allosecurinine (see scheme). The synthesis proceeds with enantiomeric purity in 15 steps with a...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2008-09, Vol.47 (41), p.7945-7948
Hauptverfasser:	Leduc, Andrew B, Kerr, Michael A
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaloids Alkaloids - chemical synthesis asymmetric synthesis Azepines Euphorbiaceae - chemistry heterocycles Heterocyclic Compounds, Bridged-Ring - chemical synthesis Lactones natural products Piperidines Pyrrolidines - chemistry total synthesis
Online-Zugang:	Volltext
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