Strong Induction of Members of the Chitinase Family of Proteins in Atherosclerosis: Chitotriosidase and Human Cartilage gp-39 Expressed in Lesion Macrophages

Atherosclerosis is initiated by the infiltration of monocytes into the subendothelial space of the vessel wall and subsequent lipid accumulation of the activated macrophages. The molecular mechanisms involved in the anomalous behavior of macrophages in atherogenesis have only partially been disclose...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 1999-03, Vol.19 (3), p.687-694
Hauptverfasser:	Boot, Rolf G, van Achterberg, Tanja A.E, van Aken, Benien E, Renkema, G. Herma, Jacobs, Michael J.H.M, Aerts, Johannes M.F.G, de Vries, Carlie J.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - genetics Acid Phosphatase - metabolism Adipokines Aged Aged, 80 and over Aorta - cytology Aorta - enzymology Arteriosclerosis - metabolism Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cartilage - enzymology Cells, Cultured Chitinase-3-Like Protein 1 Chitinases - genetics Chitinases - metabolism Coronary Vessels - cytology Coronary Vessels - enzymology Female Femoral Artery - cytology Femoral Artery - enzymology Gene Expression Regulation, Enzymologic Glycoproteins - genetics Glycoproteins - metabolism Hexosaminidases - genetics Hexosaminidases - metabolism Humans Iliac Artery - cytology Iliac Artery - enzymology In Situ Hybridization Isoenzymes - genetics Isoenzymes - metabolism Lectins Macrophages - cytology Macrophages - enzymology Male Medical sciences Middle Aged Osteopontin RNA, Messenger - metabolism Sialoglycoproteins - genetics Sialoglycoproteins - metabolism Tartrate-Resistant Acid Phosphatase Umbilical Arteries - cytology Umbilical Arteries - enzymology
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