Expression of the E2 envelope glycoprotein of bovine viral diarrhoea virus (BVDV) elicits virus-type specific neutralising antibodies

A region of genome from the NADL strain of BVDV corresponding to the coding sequence for the E2 glycoprotein has been molecularly cloned using RT-PCR. The viral cDNA sequence was used to construct vaccinia virus recombinants that expressed either the entire E2 coding sequence or fragments of it. The...

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Veröffentlicht in:	Veterinary microbiology 1999-03, Vol.65 (2), p.87-101
Hauptverfasser:	Toth, R.L., Nettleton, P.F., McCrae, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	AGNEAU Animals ANTIBODIES Antibodies, Monoclonal Antibodies, Viral - blood Antibodies, Viral - immunology ANTICORPS ANTICUERPOS ANTIGENE RECOMBINANT ANTIGENOS RECOMBINANTES Base Sequence Biological and medical sciences BOVINE DIARRHOEA PESTIVIRUS bovine viral diarrhea virus Bovine viral diarrhoea virus Bovine Virus Diarrhea-Mucosal Disease - immunology Cattle CORDERO Diarrhea Viruses, Bovine Viral - chemistry Diarrhea Viruses, Bovine Viral - genetics Diarrhea Viruses, Bovine Viral - immunology EXPRESION GENICA EXPRESSION DES GENES Fundamental and applied biological sciences. Psychology GENE EXPRESSION Gene Expression Regulation, Viral Germ-Free Life - immunology LAMBS MICE Mice, Inbred BALB C Mice, Inbred C57BL Microbiology Molecular Sequence Data Neutralization Tests - veterinary Pestivirus PESTIVIRUS DE LA DIARREA BOVINA PESTIVIRUS MALADIE DES MUQUEUSES Radioimmunoprecipitation Assay - veterinary RATON RECOMBINANT ANTIGENS Sequence Analysis, DNA Sheep SOURIS VACCIN Vaccination - veterinary Vaccine VACCINES Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Synthetic Vaccinia virus Vaccinia virus recombinants VACUNA Viral Envelope Proteins - chemistry Viral Envelope Proteins - genetics Viral Envelope Proteins - immunology Virology
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