Mechanistically Inspired Catalysts for Enantioselective Desymmetrizations by Olefin Metathesis
In asymmetric olefin metathesis reactions, the addition of halide additives is often required to augment enantioselectivities, despite the fact that the additives result in catalysts with diminished reactivities. The preparation of new chiral Ru‐based catalysts was accomplished by exploiting previou...
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| Veröffentlicht in: | Chemistry : a European journal 2008-09, Vol.14 (28), p.8690-8695 |
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| container_issue | 28 |
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| container_title | Chemistry : a European journal |
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| creator | Fournier, Pierre-André Savoie, Jolaine Stenne, Brice Bédard, Marion Grandbois, Alain Collins, Shawn K. |
| description | In asymmetric olefin metathesis reactions, the addition of halide additives is often required to augment enantioselectivities, despite the fact that the additives result in catalysts with diminished reactivities. The preparation of new chiral Ru‐based catalysts was accomplished by exploiting previously reported mechanistic studies. The catalysts possess a high level of reactivity and successfully induce high levels of asymmetry in desymmetrization reactions without the use of halide additives.
It goes without…︁! New chiral Ru‐based catalysts were prepared by exploiting previously reported mechanistic studies. The catalysts possess a high level of reactivity and successfully induce high levels of asymmetry in desymmetrization reactions without the use of halide additives (see scheme). |
| doi_str_mv | 10.1002/chem.200800642 |
| format | Article |
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It goes without…︁! New chiral Ru‐based catalysts were prepared by exploiting previously reported mechanistic studies. The catalysts possess a high level of reactivity and successfully induce high levels of asymmetry in desymmetrization reactions without the use of halide additives (see scheme).</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><pmid>18688840</pmid><doi>10.1002/chem.200800642</doi><tpages>6</tpages></addata></record> |
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| subjects | Alkenes - chemistry asymmetric catalysis Catalysis desymmetrization N-heterocyclic carbenes olefin metathesis ruthenium Stereoisomerism |
| title | Mechanistically Inspired Catalysts for Enantioselective Desymmetrizations by Olefin Metathesis |
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