Use of YbIII-Centered Near-Infrared (NIR) Luminescence To Determine the Hydration State of a 3,2-HOPO-Based MRI Contrast Agent
The synthesis, structure, and characterization of a [Yb(Tren-Me-3,2-HOPO)(H2O)2] complex are reported. As a result of its YbIII emission in the near-infrared region, sensitized by the Me-3,2-HOPO chromophore, this complex can be utilized for the first time to determine the hydration state, q, via th...
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| Veröffentlicht in: | Inorganic chemistry 2008-10, Vol.47 (19), p.8571-8573 |
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| container_title | Inorganic chemistry |
| container_volume | 47 |
| creator | Moore, Evan G Seitz, Michael Raymond, Kenneth N |
| description | The synthesis, structure, and characterization of a [Yb(Tren-Me-3,2-HOPO)(H2O)2] complex are reported. As a result of its YbIII emission in the near-infrared region, sensitized by the Me-3,2-HOPO chromophore, this complex can be utilized for the first time to determine the hydration state, q, via the luminescence lifetimes and hence the solution structure of these Me-3,2-HOPO-type ligands, which have attracted significant interest in complex with GdIII as possible next-generation magnetic resonance imaging contrast agents. |
| doi_str_mv | 10.1021/ic801060x |
| format | Article |
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| source | MEDLINE; ACS Publications |
| subjects | Contrast Media - chemical synthesis Contrast Media - chemistry Infrared Rays Luminescence Magnetic Resonance Imaging Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Pyridones - chemistry Water - chemistry Ytterbium - chemistry |
| title | Use of YbIII-Centered Near-Infrared (NIR) Luminescence To Determine the Hydration State of a 3,2-HOPO-Based MRI Contrast Agent |
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