Association of Toll-like Receptor 4 Gene Polymorphisms with Normal Tension Glaucoma

Toll-like receptor 4 (TLR4) is a transmembrane receptor that mediates immune responses to exogenous and endogenous ligands and interacts with heat shock proteins, which are reportedly involved in normal tension glaucoma (NTG). This study was undertaken to investigate whether TLR4 polymorphisms are a...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2008-10, Vol.49 (10), p.4453-4457
Hauptverfasser:	Shibuya, Etsuko, Meguro, Akira, Ota, Masao, Kashiwagi, Kenji, Mabuchi, Fumihiko, Iijima, Hiroyuki, Kawase, Kazuhide, Yamamoto, Tetsuya, Nakamura, Makoto, Negi, Akira, Sagara, Takeshi, Nishida, Teruo, Inatani, Masaru, Tanihara, Hidenobu, Aihara, Makoto, Araie, Makoto, Fukuchi, Takeo, Abe, Haruki, Higashide, Tomomi, Sugiyama, Kazuhisa, Kanamoto, Takashi, Kiuchi, Yoshiaki, Iwase, Aiko, Ohno, Shigeaki, Inoko, Hidetoshi, Mizuki, Nobuhisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Eye and associated structures. Visual pathways and centers. Vision Female Fundamental and applied biological sciences. Psychology Gene Frequency Genotype Glaucoma and intraocular pressure Glaucoma, Open-Angle - genetics Haplotypes Humans Linkage Disequilibrium Male Medical sciences Middle Aged Ophthalmology Polymorphism, Single Nucleotide Reverse Transcriptase Polymerase Chain Reaction Risk Factors Toll-Like Receptor 4 - genetics Vertebrates: nervous system and sense organs
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