Involvement of CXCL12 and CXCR4 in Lymph Node Metastases and Development of Oral Squamous Cell Carcinomas

The chemokine stromal cell-derived factor (SDF-1/CXCL12) and its specific receptor, CXCR4, have been implicated in the regulation of tumor growth and organ-specific spread. The aim of this study was to determine the expression of CXCL12 and CXCR4 in samples obtained from primary squamous cell carcin...

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Veröffentlicht in:	Tumor biology 2008-01, Vol.29 (4), p.262-271
Hauptverfasser:	Oliveira-Neto, Helenisa Helena, Silva, Erica Tatiane, Leles, Cláudio Rodrigues, Mendonça, Elismauro Francisco, Alencar, Rita de Cássia, Silva, Tarcília Aparecida, Batista, Aline Carvalho
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Chemokine CXCL12 - analysis Chemokine CXCL12 - genetics Chemokine CXCL12 - physiology Female Humans Lymphatic Metastasis Male Middle Aged Mouth Neoplasms - mortality Mouth Neoplasms - pathology Receptors, CXCR4 - analysis Receptors, CXCR4 - genetics Receptors, CXCR4 - physiology Research Article
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