Mammalian 105 kDa heat shock family proteins suppress hydrogen peroxide-induced apoptosis through a p38 MAPK-dependent mitochondrial pathway in HeLa cells

Hsp105α and Hsp105β are major heat shock proteins in mammalian cells that belong to a subgroup of the HSP70 family, HSP105/110. Previously, we have shown that Hsp105α has opposite effects on stress-induced apoptosis depending on the cell type. However, it is not fully understood how Hsp105 regulates...

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