Activation of the adult mode of ovine growth hormone receptor gene expression by cortisol during late fetal development

ABSTRACT The developmental and tissue‐specific regulation of growth hormone receptor (GHR) mRNA expression is complex and involves alternate leader exon usage. The transcript composition of hepatic GHR mRNA has therefore been determined in fetal sheep during late gestation and after experimental man...

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Veröffentlicht in:	The FASEB journal 1999-03, Vol.13 (3), p.545-552
Hauptverfasser:	Li, J. (University of Cambridge, Cambridge.), Gilmour, R.S, Saunders, J.C, Dauncey, M.J, Fowden, A.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenalectomy Animals Embryonic and Fetal Development Exons fetal plasma Cortisol fetus Gene Expression Regulation, Developmental - drug effects GH binding GHR glucocorticoid response element HORMONE RECEPTORS Hydrocortisone - blood Hydrocortisone - pharmacology Hydrocortisone - physiology insulin-like growth factor Liver - embryology OVIN OVINOS RECEPTEUR D'HORMONE RECEPTORES DE HORMONAS Receptors, Somatotropin - genetics riboprobe SHEEP Sheep - embryology SOMATOTROPIN SOMATOTROPINA SOMATOTROPINE Time Factors
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