ENDOTHELIUM-DERIVED HYPERPOLARIZING FACTOR(S): SPECIES AND TISSUE HETEROGENEITY

1. Endothelium‐derived relaxing factor is almost universally considered to be synonymous with nitric oxide (NO); however, it is now well established that at least two other chemically distinct species (prostacyclin (PGI2) and a hyperpolarizing factor) may also contribute to endothelium‐dependent rel...

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Veröffentlicht in:	Clinical and experimental pharmacology & physiology 1999-02, Vol.26 (2), p.176-179
Hauptverfasser:	Triggle, CR, Waldron, H Dong, Gj, Cole, WC
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Factors - metabolism Carotid Arteries - metabolism Cerebral Arteries - metabolism cytochrome P450 endothelium endothelium- derived relaxing factor Epoprostenol - metabolism epoxyeicosatrienoic acid Guinea Pigs hyperpolarizing factor K+ channels Mesenteric Arteries - metabolism nitric oxide Nitric Oxide - metabolism prostacyclin Rabbits Species Specificity Tissue Distribution vascular smooth muscle
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