Human antibody responses to A and C capsular polysaccharides, IgA1 protease and transferrin–binding protein complex stimulated by infection with Neisseria meningitidis of subgroup IV-1 or ET-37 complex

The protein sequences of the IgA1 protease, TbpA and TbpB proteins differ between meningococci representative of serogroup A, subgroup IV-1 from epidemic disease in The Gambia and serogroup C, ET-37 complex from endemic disease in Mali. The uniformity of restriction endonuclease sites was determined...

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Veröffentlicht in:	Vaccine 1999-02, Vol.17 (7), p.731-744
Hauptverfasser:	Brieske, Norbert, Schenker, Martin, Schnibbe, Thomas, Quentin-Millet, Marie-José, Achtman, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibodies, Bacterial - biosynthesis Antigens, Bacterial - immunology Bacteriology Biological and medical sciences Carrier Proteins - immunology Epidemiology Epitopes - immunology Fundamental and applied biological sciences. Psychology Gambia - epidemiology Humans Immunogenicity Immunoglobulin G - biosynthesis Immunoglobulin G - immunology Invasive disease Iron-Binding Proteins Meningitis, Meningococcal - blood Meningitis, Meningococcal - epidemiology Meningitis, Meningococcal - immunology Meningococci Microbiology Molecular Sequence Data Nasopharyngeal carriage Nasopharynx - microbiology Neisseria meningitidis Neisseria meningitidis - classification Neisseria meningitidis - immunology Neisseria meningitidis - isolation & purification Polysaccharides, Bacterial - immunology Serine Endopeptidases - immunology Transferrin-Binding Proteins Vaccine development
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