Tight glycemic control does not affect asymmetric-dimethylarginine in septic patients

Objective We investigated whether preventing hyperglycemia in septic patients affected the plasma concentration of asymmetric-dimethylarginine and if this was associated with clinical benefit. Design A prospective, multicenter, randomized, controlled, clinical study. Setting Intensive care units (IC...

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Veröffentlicht in:	Intensive care medicine 2008-10, Vol.34 (10), p.1843-1850
Hauptverfasser:	Iapichino, Gaetano, Albicini, Maura, Umbrello, Michele, Sacconi, Francesca, Fermo, Isabella, Pavlovich, Radmila, Paroni, Rita, Bellani, Giacomo, Mistraletti, Giovanni, Cugno, Massimo, Pesenti, Antonio, Gattinoni, Luciano
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthesiology Arginine - analogs & derivatives Arginine - blood Biological and medical sciences Clinical death. Palliative care. Organ gift and preservation Critical Care Medicine Cytokines Emergency Medicine Female Glucose Humans Hyperglycemia Hyperglycemia - complications Hyperglycemia - drug therapy Hypoglycemic Agents - therapeutic use Insulin Insulin - therapeutic use Intensive Intensive care Intensive care medicine Intensive Care Units Male Medical sciences Medicine Medicine & Public Health Metabolism Middle Aged Mortality Nitric oxide Oxidative stress Pain Medicine Pediatrics Plasma Pneumology/Respiratory System Proteins Pulmonary hypertension Sepsis Sepsis - blood Sepsis - complications Treatment Outcome Tumor necrosis factor-TNF Ôriginal
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