Total Synthesis of an Anti-Helicobacter pylori Agent, Actinopyrone A

Actinopyrone A, an anti‐Helicobacter pylori agent, was synthesized in nine steps from a silyl dienol ether. A vinylogous anti‐aldol was stereoselectively synthesized by our developed remote stereoinduction methodology; coupling of this with a sulfone and a phosphonate species led to the construction...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemistry, an Asian journal an Asian journal, 2008-09, Vol.3 (8-9), p.1415-1421
Hauptverfasser:	Hosokawa, Seijiro, Yokota, Kazuya, Imamura, Keisuke, Suzuki, Yasuaki, Kawarasaki, Masataka, Tatsuta, Kuniaki
Format:	Artikel
Sprache:	eng
Schlagworte:	actinopyrone A aldol reaction Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Helicobacter pylori - drug effects Models, Molecular Molecular Structure Pyrones - chemical synthesis Pyrones - chemistry Pyrones - pharmacology remote stereoinduction structural determination total synthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!