Principles of protein folding in the cellular environment
The ability of newly synthesised protein chains to fold into their functional conformations has evolved within the complex intracellular environment. Until recently, however, this ability has been studied largely as the refolding of denatured mature proteins in dilute simple solutions. Recent work a...
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| Veröffentlicht in: | Current opinion in structural biology 1999-02, Vol.9 (1), p.102-110 |
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| container_end_page | 110 |
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| container_issue | 1 |
| container_start_page | 102 |
| container_title | Current opinion in structural biology |
| container_volume | 9 |
| creator | Ellis, R John Hartl, F Ulrich |
| description | The ability of newly synthesised protein chains to fold into their functional conformations has evolved within the complex intracellular environment. Until recently, however, this ability has been studied largely as the refolding of denatured mature proteins in dilute simple solutions. Recent work aimed at understanding how proteins fold in vivo has allowed some general statements to be postulated. |
| doi_str_mv | 10.1016/S0959-440X(99)80013-X |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Current opinion in structural biology, 1999-02, Vol.9 (1), p.102-110 |
| issn | 0959-440X 1879-033X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69598995 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Biological Evolution Cell Compartmentation Eukaryotic Cells Models, Chemical Molecular Chaperones - metabolism Protein Biosynthesis Protein Folding Proteins - chemistry Proteins - genetics Space life sciences |
| title | Principles of protein folding in the cellular environment |
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