Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13

Jane Worthington and colleagues report that three SNPs, located on chromosomes 10p15, 12q13 and 22q13, are associated with susceptibility to rheumatoid arthritis. These SNPs had previously been putatively associated with rheumatoid arthritis in the genome-wide association study conducted by the Well...

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Veröffentlicht in:	Nature genetics 2008-10, Vol.40 (10), p.1156-1159
Hauptverfasser:	Barton, Anne, Thomson, Wendy, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, Plant, Darren, Gibbons, Laura J, Wilson, Anthony G, Bax, Deborah E, Morgan, Ann W, Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M, Wordsworth, Paul, Harrison, Pille, Worthington, Jane
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animal Genetics and Genomics Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - pathology Biomedical and Life Sciences Biomedicine brief-communication Cancer Research Case-Control Studies Chromosome Mapping Chromosomes Chromosomes, Human, Pair 10 - genetics Chromosomes, Human, Pair 12 - genetics Chromosomes, Human, Pair 22 - genetics Data analysis Diabetes Disease susceptibility Gene Function Genetic aspects Genetic Linkage Genetic Predisposition to Disease - genetics Human Genetics Humans Kinases Polymorphism, Single Nucleotide - genetics Rheumatoid arthritis Risk factors Sample size Single nucleotide polymorphisms Validation studies
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