Positive regulation of migration and invasion by vasodilator-stimulated phosphoprotein via Rac1 pathway in human breast cancer cells

This study aimed to investigate the role of the cytoskeleton-associated protein vasodilator-stimulated phosphoprotein (VASP) on the migration and invasion of human breast cancer cells and its relationship to Rac1 which is a member of the Rho family and has been found to be implicated in tumorigenesi...

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Veröffentlicht in:	Oncology reports 2008-10, Vol.20 (4), p.929-939
Hauptverfasser:	Han, Guoge, Fan, Biao, Zhang, Yimin, Zhou, Xuan, Wang, Yongping, Dong, Huimin, Wei, Yun, Sun, Shengrong, Hu, Mingbo, Zhang, Jingwei, Wei, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast Neoplasms - pathology Cell Adhesion Molecules - antagonists & inhibitors Cell Adhesion Molecules - physiology Cell Line, Tumor Cell Movement Female Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Microfilament Proteins - antagonists & inhibitors Microfilament Proteins - physiology N-Formylmethionine Leucyl-Phenylalanine - pharmacology Neoplasm Invasiveness Phosphoproteins - antagonists & inhibitors Phosphoproteins - physiology rac1 GTP-Binding Protein - antagonists & inhibitors rac1 GTP-Binding Protein - physiology RNA, Small Interfering - pharmacology Signal Transduction Tumors
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