Insolubilization of water-soluble dextran

In order to clarify the insolubilization mechanism of water-soluble dextran, comparison of water-soluble dextran and insoluble particles was carried out by detailed structural and surface chemical studies. The precipitate that form in bottled dextran solutions are composed of dextran itself, resulti...

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Veröffentlicht in:Biomaterials 1999-02, Vol.20 (4), p.303-307
Hauptverfasser: Hirata, Yuuki, Aoki, Mitsuo, Kobatake, Hideki, Yamamoto, Hiroyuki
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container_title Biomaterials
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creator Hirata, Yuuki
Aoki, Mitsuo
Kobatake, Hideki
Yamamoto, Hiroyuki
description In order to clarify the insolubilization mechanism of water-soluble dextran, comparison of water-soluble dextran and insoluble particles was carried out by detailed structural and surface chemical studies. The precipitate that form in bottled dextran solutions are composed of dextran itself, resulting from the interaction of dextran molecules (e.g., the formation of hydrogen bonds). Interaction of dextran molecules derived from a crystallized domain causes insolubilization from aqueous solution. In addition, the adsorption of dextran molecules on the air-liquid interface is the first step of insolubilization.
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adsorption
Biological and medical sciences
Calorimetry, Differential Scanning
Carbon Isotopes
Chemical Precipitation
Chromatography, High Pressure Liquid
Crystallization
Dextran
Dextrans - chemistry
DSC
Hydrogen bonds
Hydrolysis
Insolubilization
Medical sciences
Molecular structure
NMR
Nuclear Magnetic Resonance, Biomolecular
Phase interfaces
Plasma Substitutes - chemistry
Polysaccharides
Precipitation (chemical)
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Reaction kinetics
Solubility
Solutions
Surface chemistry
Surface excess
Technology. Biomaterials. Equipments. Material. Instrumentation
Water - chemistry
title Insolubilization of water-soluble dextran
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