Expression of MFA1 and STE6 is sufficient for mating type-independent secretion of yeast a-factor, but not mating competence

The yeast a-factor mating peptide and its transporter Ste6 are normally expressed only in MATa haploid cells. The a-factor is initially produced as a 36- or 38-residue peptide precursor and must undergo extensive post-translational processing to produce an active 12 amino-acid lipopeptide. To better...

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Veröffentlicht in:	Current genetics 1999-02, Vol.35 (1), p.1-7
Hauptverfasser:	Quinby, G.E, Dean, J.P, Deschenes, R.J
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporters ATP-Binding Cassette Transporters - genetics binding proteins Fungal Proteins - genetics gene expression Gene Expression Regulation, Fungal - genetics genes Genes, Fungal - genetics Genes, Mating Type, Fungal Genotype Glycoproteins Infertility - genetics mating behavior Mating Factor messenger RNA peptides Peptides - genetics Pheromones Ploidies precursors Protein Precursors - genetics Protein Processing, Post-Translational - genetics protein secretion protein transport RNA, Messenger - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins sexual reproduction
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