Integrin Trafficking Regulated by Rab21 Is Necessary for Cytokinesis

Adherent cells undergo remarkable changes in shape during cell division. However, the functional interplay between cell adhesion turnover and the mitotic machinery is poorly understood. The endo/exocytic trafficking of integrins is regulated by the small GTPase Rab21, which associates with several i...

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Veröffentlicht in:	Developmental cell 2008-09, Vol.15 (3), p.371-385
Hauptverfasser:	Pellinen, Teijo, Tuomi, Saara, Arjonen, Antti, Wolf, Maija, Edgren, Henrik, Meyer, Hannelore, Grosse, Robert, Kitzing, Thomas, Rantala, Juha K., Kallioniemi, Olli, Fässler, Reinhard, Kallio, Marko, Ivaska, Johanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Cell Adhesion - physiology Cell Cycle - physiology Cell cycle, cell proliferation Cell differentiation, maturation, development, hematopoiesis Cell Line Cell physiology CELLBIO Cricetinae Cricetulus Cytokinesis - physiology Endocytosis - physiology Fundamental and applied biological sciences. Psychology Humans Integrin alpha Chains - genetics Integrin alpha Chains - metabolism Integrin beta1 - genetics Integrin beta1 - metabolism Laminin - metabolism Mice Molecular and cellular biology Molecular Sequence Data Neoplasms - genetics Neoplasms - metabolism rab GTP-Binding Proteins - genetics rab GTP-Binding Proteins - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism rhoA GTP-Binding Protein - genetics rhoA GTP-Binding Protein - metabolism Sequence Alignment Vitronectin - metabolism
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