Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation

The ethanolamides of arachidonic, myristic and linoleic acids reduce bone marrow cell migration, while the 2-glyceryl esters of these acids enhance migration. Thus the 2 major endocannabinoids, anandamide (arachidonoyl ethanolamide) and 2-AG (2-arachidonoyl glycerol), whose structural difference lie...

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Veröffentlicht in:	European journal of pharmacology 2008-10, Vol.595 (1), p.1-6
Hauptverfasser:	Patinkin, Deborah, Milman, Garry, Breuer, Aviva, Fride, Ester, Mechoulam, Raphael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Marrow Cells - metabolism Cannabinoid receptor CB 1 Cannabinoid receptor CB 2 Cannabinoid Receptor Modulators - metabolism Cell Differentiation Cell Movement Cell Proliferation Cells, Cultured Colony-Forming Units Assay Endocannabinoids Ethanolamide cannabinoids Glycerol - analogs & derivatives Glycerol - metabolism Glycerol cannabinoids Hematopoietic Stem Cells - metabolism Medical sciences Mice Mice, Inbred C3H Pharmacology. Drug treatments Polyunsaturated Alkamides - metabolism Receptor, Cannabinoid, CB1 - metabolism Receptor, Cannabinoid, CB2 - metabolism
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