Effects of Age and Gender on Cardiovascular Responses to Phenylephrine

Background. The age-associated impairment in left ventricular (LV) systolic function appears to be mostly detectable during exercise or sympathetic stimulation. We hypothesized that the decline in cardiac function could be unmasked by an acute increase in afterload induced by phenylephrine. We furth...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 1999-01, Vol.54 (1), p.M17-M24
Hauptverfasser:	Turner, Michael J., Mier, Constance M., Spina, Robert J., Ehsani, Ali A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology Adult Aged Aging Aging - physiology Atropine - pharmacology Blood Pressure - drug effects Cardiac Output - drug effects Cardiac Output - physiology Circulatory system Diastole Echocardiography Exercise Female Gerontology Heart Heart - drug effects Heart Rate - drug effects Heart Ventricles - anatomy & histology Heart Ventricles - drug effects Humans Male Middle Aged Muscarinic Antagonists - pharmacology Myocardial Contraction - drug effects Phenylephrine - pharmacology Physical Exertion - physiology Sex Factors Sexes Space life sciences Sympathetic Nervous System - physiopathology Systole Vagus Nerve - drug effects Ventricular Function, Left - drug effects Ventricular Function, Left - physiology
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