Cytosolic RAB3D is associated with RAB escort protein (REP), not RAB-GDP dissociation inhibitor (GDI), in dispersed chief cells from guinea pig stomach

Rab3D, a low‐molecular‐weight GTP‐binding protein believed to be involved with regulated exocytosis, is associated with secretory granules in gastric chief cells. Although Rab3D is predominantly membrane associated, a significant fraction is cytosolic. Rab proteins are geranylgeranylated on their C‐...

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Veröffentlicht in:	Journal of cellular biochemistry 1999-03, Vol.72 (4), p.540-548
Hauptverfasser:	Raffaniello, Robert D., Raufman, Jean-Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkyl and Aryl Transferases Animals Brain - metabolism Carrier Proteins - metabolism Chief Cells, Gastric - metabolism Chromatography, Gel Cytoplasmic Granules - metabolism Exocytosis geranylgeranylation GTP-Binding Proteins - metabolism Guanine Nucleotide Dissociation Inhibitors Guinea Pigs Male membrane targeting Protein Prenylation rab GTP-Binding Proteins Rab proteins rab3 GTP-Binding Proteins rho-Specific Guanine Nucleotide Dissociation Inhibitors secretion
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