Folate receptor type β is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia

BACKGROUND The membrane‐associated folate receptor (FR) type β is elevated in the spleen in patients with chronic myeloid leukemia (CML) and acute myeloid leukemia (AML). In this study, the authors investigated possible cell type and differentiation stage specificity of expression of FR‐β in normal...

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Veröffentlicht in:	Cancer 1999-01, Vol.85 (2), p.348-357
Hauptverfasser:	Ross, John F., Wang, Hui, Behm, Frederick G., Mathew, Prasad, Wu, Marietta, Booth, Robert, Ratnam, Manohar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - analysis Antigens, Differentiation - biosynthesis Biological and medical sciences Biomarkers Blood/Bone Marrow Carrier Proteins - biosynthesis Carrier Proteins - immunology CD antigens Cell Differentiation CHO Cells Cricetinae differentiation marker folate receptor Folate Receptors, GPI-Anchored Hematologic and hematopoietic diseases Humans Immunohistochemistry leukemia Leukemia, Myeloid - metabolism Leukemia, Myeloid - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Leukocytes, Mononuclear - metabolism Medical sciences Neutrophils - cytology Rabbits Receptors, Cell Surface
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