Cloning and functional characterization of the 5'-flanking region of the human monocyte chemoattractant protein-1 receptor (CCR2) gene. Essential role of 5'-untranslated region in tissue-specific expression

The human monocyte chemoattractant protein-1 receptor designated hCCR2 is an essential co-receptor in cell entry by the human immunodeficiency virus as well as a receptor for monocyte chemoattractant protein-1, a member of the family of C-C chemokines that mediate monocyte chemotaxis. To elucidate t...

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Veröffentlicht in:	The Journal of biological chemistry 1999-02, Vol.274 (8), p.4646-4654
Hauptverfasser:	Yamamoto, K, Takeshima, H, Hamada, K, Nakao, M, Kino, T, Nishi, T, Kochi, M, Kuratsu, J, Yoshimura, T, Ushio, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions AIDS/HIV Alternative Splicing Base Sequence CCAAT-Enhancer-Binding Proteins Chemokine CCL2 - metabolism Cloning, Molecular DNA, Complementary DNA-Binding Proteins - metabolism Host Cell Factor C1 Humans Molecular Sequence Data Nuclear Proteins - metabolism Octamer Transcription Factor-1 Protein Binding Receptors, CCR2 Receptors, Chemokine - genetics Receptors, Chemokine - metabolism Transcription Factors - metabolism Transcriptional Activation Tumor Cells, Cultured
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