Nitric Oxide/cAMP Interactions in the Control of Rat Renal Vascular Resistance

This study aimed to characterize the interaction between nitric oxide (NO)- and cAMP-related pathways in the control of renal blood flow. Using the isolated perfused rat kidney model, we determined the effects of inhibition of NO formation by N methyl ester (L-NAME; 1 mmol/L) and of NO administratio...

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Veröffentlicht in:	Circulation research 1999-02, Vol.84 (2), p.186-192
Hauptverfasser:	Sandner, Peter, Kornfeld, Mark, Ruan, Xiaoping, Arendshorst, William J, Kurtz, Armin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - drug effects Animals Arterioles - drug effects Biological and medical sciences Cyclic AMP - metabolism Cyclic GMP - analogs & derivatives Cyclic GMP - pharmacology Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Hemodynamics. Rheology In Vitro Techniques Kidney - blood supply Male NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - metabolism Nitroprusside - pharmacology Perfusion Rats Rats, Sprague-Dawley Stimulation, Chemical Vertebrates: cardiovascular system
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